![]() Anxiety-like behavior in the open field was significantly and negatively correlated with walking time in the beam-walking test. Under another anxiogenic situation, in a beam walking test, the EE rats more quickly traversed an elevated narrow beam. After 5 weeks of rearing, the EE rats showed decreased anxiety-like behavior in an open field than the SE rats. ![]() Three-week-old male rats were divided into two groups: those reared in an enriched environment (EE rats) and those reared in standard cages (SE rats). Here we investigated whether rearing in enriched environment could modify the expression of parvalbumin-positive neurons in the basolateral amygdala and anxiety-like behavior. ![]() In particular, alteration of parvalbumin-expressing neurons, a gamma-aminobutyric acid (GABA)ergic neuronal subpopulation, has been suggested to be associated with psychiatric disorders. ![]() Early life experiences including physical exercise, sensory stimulation, and social interaction can modulate development of the inhibitory neuronal network and modify various behaviors. ![]()
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